Compounds and conjugates thereof
US11446292B2 · kind B2 · utility
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10References
15Claims
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Key dates
| Filing date | Jun 15, 2021 |
| Grant date | Sep 20, 2022 |
| Priority date | — |
| Expiry date | Jun 15, 2041 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A conjugate comprising the following topoisomerase inhibitor derivative (A*): with a linker for connecting to a Ligand Unit, wherein the linker is attached in a cleavable manner to the amino residue. The Ligand Unit is preferably an antibody. Also provided is A* with the linking unit attached, and intermediates for their synthesis, as well as the released warhead.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.