Method and apparatus for single particle deposition

US11446651B2 · kind B2 · utility

Assignee

• Scienion GmbH · DE

Inventors

• Guilhem Arnaud Tourniaire · L'Essart Mador, FR
• Ophelie Isabelle Berthuy · Diémoz, FR
• Francois Monjaret · Villeurbanne, FR
• Joshua CANTLON-BRUCE · Phoenix, US
• Gianluigi Atzeni · L'Essart Mador, FR
• Illia Glavatskyi · Berlin, DE

Key dates

• Filing date: Sep 7, 2018
• Grant date: Sep 20, 2022
• Expiry date: Nov 3, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2035/1062
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method and droplet dispenser for depositing single particles onto a target. For example, a single particle depositing method with improved rate of dispensing single particles and/or increased recovery of rare particles and/or with an extended applicability with different types of particles and/or operation conditions. The depositing method may be capable of increasing the rate of dispensing single cells without decreasing the recovery rate. Testing a single particle condition is combined with testing a zero particle condition and/or the particle type condition. The ejection and sedimentation regions are tested with regard to the presence of a single particle in the ejection, and further particle arrangements allowing a single particle deposition are identified and tested and/or the particle type detection is added to the dispenser control. Accordingly, the speed and recovery rate of dispensing single particles of interest can be improved.