Patent · US Active

In vitro methods of chemical conversion using non-stereospecific glutathione lyases

US11447754B2 · kind B2 · utility

0Cited by

6References

21Claims

0Family size

Assignee

Wisconsin Alumni Research Foundation · US

Inventors

Timothy James Donohue · Menlo Park, US
Daniel Leo Gall · Troy, US
Wayne S. Kontur · Madison, US
Hoon Kim · New Providence, US
John Ralph · Madison, US
Daniel R. Noguera · Madison, US
Brian G. Fox · Madison, US
Craig Bingman · Madison, US

Key dates

Filing date	Sep 30, 2020
Grant date	Sep 20, 2022
Priority date	—
Expiry date	Dec 4, 2040

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/582
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, β-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The β-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.