Serine protease variants and polynucleotides encoding same
US11447763B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2021 |
| Grant date | Sep 20, 2022 |
| Priority date | — |
| Expiry date | Jan 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.