Production in plants of ricin antibodies that bind to ricin B chain
US11447789B2 · kind B2 · utility
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Key dates
| Filing date | Dec 1, 2016 |
| Grant date | Sep 20, 2022 |
| Priority date | — |
| Expiry date | Dec 1, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of making an antibody in plants that binds to ricin B chain is described. The method comprises (a) introducing a nucleic acid molecule encoding a heavy chain variable region of the antibody and a nucleic acid molecule encoding a light chain variable region of the antibody into a plant or plant cell; and (b) growing the plant or plant cell to obtain a plant that expresses the antibody or antibody fragment. The disclosure also relates to anti-ricin B chain antibodies and antibody fragments as well as methods of using same in therapy and prophylaxis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.