Compositions and methods for the production of compounds

US11447810B2 · kind B2 · utility

Assignee

• Ginkgo Bioworks, Inc. · US

Inventors

• Brian Roger Bowman · New Rochelle, US
• Joshua A. V. Blodgett · Webster Groves, US
• Gregory L. Verdine · Boston, US
• Daniel C. Gray · Medford, US
• Jay P. Morgenstern · Boston, US
• Lucy Foulston · Medford, US
• Keith E. Robison · Wilmington, US

Key dates

• Filing date: Jan 29, 2021
• Grant date: Sep 20, 2022
• Expiry date: Feb 27, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y114/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present disclosure provides nucleic acids encoding a Large ATP-binding regulator of the LuxR family (LAL) of transcription factors, vectors and host cells including such nucleic acids, and methods for producing compounds (e.g., polyketides or β-lactam compounds) with such nucleic acids, vectors, and/or host cells.