Methods for the analysis of proximity binding assay data
US11447815B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 20, 2018 |
| Grant date | Sep 20, 2022 |
| Priority date | — |
| Expiry date | Jul 21, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/10
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Various embodiments of methods for analyzing proximity binding assay (PBA) data are disclosed. Proximity binding assays as a class of analyses offer the advantages of the sensitivity and specificity of biorecognition binding, along with the exponential signal amplification offered by a variety of oligonucleotide amplification reactions, such as the polymerase chain reaction (PCR). However, as various proximity binding assays have reaction kinetics governed by an additional step of the binding of a biorecognition probe (BRP) with a target molecule, there is a need for methods for the analysis of PBA data that are particularly suited to the unique characteristics of such data.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.