Method of preparing bioactive substance-encapsulated ethosome, ethosome composition, and cosmetic composition including ethosome composition
US11452679B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Mar 9, 2018 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | Mar 9, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/413
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method of preparing a bioactive substance-encapsulated ethosome, the method including: preparing an aqueous solution of a bioactive substance, preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.