Oral drug delivery composition containing oxaliplatin and method for preparing same
US11452705B2 · kind B2 · utility
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Key dates
| Filing date | Nov 30, 2017 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | May 19, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/554
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are an oral delivery composition including oxaliplatin, a water-soluble anticancer agent, and a preparation method thereof, including forming an ionic complex with a bile acid derivative, which is an oral absorption promoter, and oxaliplatin, and incorporating it into the inner aqueous phase of a water-in-oil-in-water (w/o/w) multiple nanoemulsions, thereby obtaining the oral delivery composition with improved oral bioavailability of oxaliplatin, a water-soluble anticancer agent, avoiding the inconvenience and problems of injection, improving patient compliance, and reducing medical costs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.