Process for preparing modulators of p300 and/or CBP
US11453662B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Apr 18, 2019 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | Aug 12, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for producing a compound of the following formula (I) which process comprises: (a) treating a compound of the following formula (5) with a compound of the following formula (6) to generate an intermediate compound of the following formula (7); (b) treating a compound of formula (7) as defined above with a compound of the following formula (8); and (c) recovering a compound of formula (I) as defined above. The compound of formula (I) is a promising modulator of p300/CBP activity that has potential utility in treating cancers, including prostate cancer, haematological cancers, bladder cancer and lung cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.