Intensity extraction and crosstalk attenuation using interpolation and adaptation for base calling
US11455487B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 26, 2021 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | Oct 26, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V20/69
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The technology disclosed attenuates spatial crosstalk from sequencing images for base calling. The technology disclosed accesses a section of an image output by a biosensor, where the section of the image includes a plurality of pixels depicting intensity emission values from a plurality of clusters within the biosensor and from locations within the biosensor that are adjacent to the plurality of clusters. The plurality of clusters includes a target cluster. The section of the image is convolved with a convolution kernel, to generate a feature map comprising a plurality of features having a corresponding plurality of feature values. A weighted feature value is assigned to the target cluster, where the weighted feature value is based on one or more features values of the plurality of feature values of the feature map. The weighted feature value assigned to the target cluster is processed, to base call the target cluster.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.