Spatio-temporal localization for mass spectrometry sample analysis
US11456165B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 2020 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | May 20, 2041 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/26
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
In a method for spatially localizing mass-spectrometry analysis of an analyte derived from an energy event, an electrical device is used to deliver an energy event to a substrate, and the analyte produced is analyzed using mass spectrometry. Electrical signals sent to and received from the electrical device under different modes of operation are sensed and classified according to each different mode of operation. A location of the electrical device is tracked in three dimensions during the energy event, and a processor is used to perform spatial-temporal alignment of the mass-spectrometry, the determined modes of operation of the electrical device, and the tracked location of the electrical device, wherein mass spectrometry data corresponding to the determined modes of the electrical device are identified and localized within the site of the energy event. The substrate may be tissue in a surgical site, and the electrical device may be an electrocautery device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.