Patent · US Active

Compositions, systems, and methods for genome editing

US11459551B1 · kind B1 · utility

1Cited by

15References

6Claims

0Family size

Assignee

INARI AGRICULTURE TECHNOLOGY, INC. · US

Inventors

Adam Patrick Joyce · Stow, US
Michael Andreas Kock · Schifferstadt, DE
Hannah Pham · Somerville, US

Key dates

Filing date	Aug 30, 2019
Grant date	Oct 4, 2022
Priority date	—
Expiry date	Dec 21, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2800/80
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure provides compositions that include a polynucleotide including or encoding a Cas12a tracrRNA, and methods for their use in sequence-specific genome editing, especially of eukaryotic genomic sequences. In particular, this disclosure provides Cas12a tracrRNA-containing compositions and methods for their use in Cas12a-mediated editing of a target sequence, wherein the editing efficiency is increased in comparison to controls lacking the Cas12a tracrRNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.