Modulation of frataxin expression

US11459564B2 · kind B2 · utility

Assignees

• Ionis Pharmaceuticals, Inc. · US
• The Board of Regents of the University of Texas System · US

Inventors

• Frank Rigo · Carlsbad, US
• Thazha P. Prakash · Carlsbad, US
• David R. Corey · Dallas, US

Key dates

• Filing date: Dec 21, 2018
• Grant date: Oct 4, 2022
• Expiry date: Dec 21, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/51
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Certain embodiments are directed to methods and compounds for increasing FXN. Such methods and compounds are useful for increasing expression of FXN in cells and animals.