Immunomodulating and immunostimulating ecotin polypeptides from Salmonella for drug-delivery
US11459575B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 8, 2019 |
| Grant date | Oct 4, 2022 |
| Priority date | — |
| Expiry date | Feb 15, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55516
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to modified bacterial polypeptides having immunomodulatory and immunostimulatory activity. Most specifically, the present invention relates to modified bacterial polypeptides having an amino acid sequence selected from SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4 and SEQ ID NO. 5. The modified polypeptides are the adjuvant components of a pharmaceutical composition for eliciting an immune response against an specific antigen present in the pharmaceutical composition. In a preferred embodiment, the invention provides a pharmaceutical composition for a vaccine which comprises an adjuvant component which is any one of the modified polypeptides, one or more antigens, together with a pharmaceutically acceptable excipient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.