Method and system for sample collection, storage, preparation and detection

US11465145B2 · kind B2 · utility

Inventors

• Orion N. Scott · Charlottesville, US
• Christopher H. Birch · Toronto, CA
• Daniel Mills · Charlottesville, US
• Brian Root · Charlottesville, US
• James P. Landers · Charlottesville, US
• Jingyi Li · Xi'an, CN
• Matthew Yeung · Melbourne, AU
• David Saul · Auckland, NZ
• David Vigil · Worland, US
• Andrew Guy · Melbourne, AU
• Stan Wada · Melbourne, AU
• Betina De Gorordo · Melbourne, AU
• Steward Dodman · Melbourne, AU
• Tom Moran · Southampton, GB
• Stuart John Knowles · Walnut Creek, US
• Fernando Agostinho Peixoto DIAS · Melbourne, AU
• Rick Gardner · Melbourne, AU

Key dates

• Filing date: Aug 26, 2021
• Grant date: Oct 11, 2022
• Expiry date: Aug 26, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/26
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.