Process for preparing soluble guanylate cyclase stimulators
US11466014B2 · kind B2 · utility
1Cited by
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11Claims
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Assignee
Inventor
Key dates
| Filing date | Mar 7, 2019 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | Mar 17, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel methods for preparing 3-substituted 1,2,4-triazole compounds of Formula IA: as sGC stimulators. The method comprises reacting the amidrazone compound represented by Formula IIA: or a salt thereof, with a carboxylic acid, an activated ester, a thioester, an acid halide, a thioacyl halide, or an acid anhydride in the presence of a base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.