Neomycin and paromomycin derivatives
US11466044B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Apr 6, 2018 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | Nov 21, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6′, C2′ and/or C5″. The modifications impart favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits and increased selectivity, enabling systemic use of the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.