Virus-like nanoparticles for oral delivery
US11466055B2 · kind B2 · utility
1Cited by
2References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2019 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | Jun 27, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/28123
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A Hepatitis E virus (HEV)-based virus like nanoparticle (HEVNP) made with a modified capsid protein containing at least a portion of open reading frame 2 (ORF2) protein conjugated with gold nanocluster is provided. Also provided are methods of targeted delivery of a nucleic acid using the HEVNP.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.