Patent · US Active

Human serum albumin variants and uses thereof

US11466073B2 · kind B2 · utility

0Cited by

17References

6Claims

0Family size

Assignee

CSL LIMITED · AU

Inventors

Sabine Rauth · Munich, DE
Andrew HAMMET · Melbourne, AU
Kirsten Mae Edwards · Melbourne, AU
Con Panousis · Melbourne, AU

Key dates

Filing date	Oct 18, 2018
Grant date	Oct 11, 2022
Priority date	—
Expiry date	Dec 16, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/31
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A serum albumin variant, or functional fragment thereof, comprising one or more amino acid substitutions selected from (i) glycine, isoleucine, lysine, methionine, phenylalanine, tryptophan, tyrosine, valine and leucine substituted for glutamine at position (522); (ii) valine substituted for alanine at position (552); and (iii) alanine, glutamic acid, histidine, serine, lysine and arginine substituted for glycine at position (572).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.