Antibodies targeting a galactan-based O-antigen of K. pneumoniae
US11466074B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Nov 3, 2015 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | Nov 3, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of Klebsiella pneumoniae, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galactose homopolymer of Formula (I). The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.