Methods for obtaining information from single cells within populations using DNA origami nanostructures without the need for single cell sorting
US11466267B2 · kind B2 · utility
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Key dates
| Filing date | Mar 27, 2018 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | May 15, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for construction of DNA origami nanostructures, as well as for binding, isolation, linking, and deep sequencing information, such as both of TCR alpha and beta CDR3 mRNA, from individual cells within a mixed population of cells without the need for single cell sorting (FIG. 1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.