Patent · US Active

Mechanically-strained oligonucleotide constructs and methods of using the same

US11466309B2 · kind B2 · utility

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11Claims

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Assignee

THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS · US

Inventor

Yong Wang · Chesterfield, US

Key dates

Filing date	Oct 14, 2019
Grant date	Oct 11, 2022
Priority date	—
Expiry date	Aug 4, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2563/137
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are mechanically-strained oligonucleotide constructs comprising two oligonucleotides that when hybridized results in a bent double-stranded oligonucleotide. The constructs may be used to probe oligonucleotide interactions with an analyte to detect interactions with metal ions or compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.