Methods and systems for characterizing analytes using nanopores
US11466317B2 · kind B2 · utility
2Cited by
5References
10Claims
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Key dates
| Filing date | Nov 29, 2017 |
| Grant date | Oct 11, 2022 |
| Priority date | — |
| Expiry date | Dec 11, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of characterizing an analyte using a nanopore. One aspect features methods for characterizing a double-stranded polynucleotide using a nanopore, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.