Methods for treatment of H. pylori infections

US11471532B2 · kind B2 · utility

Assignees

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US
• DER WISSENSCHAFT EN E.V. · DE
• TECHNISCHE UNIVERSITÄT MÜNCHEN · DE

Inventors

• Anahita JAVAHERI · Munich, DE
• Tobias KRUSE · Munich, DE
• Markus Gerhard · Munich, DE
• Bernhard Singer · Essen, DE
• Daniel Hornburg · Foster City, US
• Han Remaut · Boutersem, BE
• Matthias Mann · Munich, DE
• Felix MEISSNER · Berlin, DE
• Steffen BACKERT · Erlangen, DE

Key dates

• Filing date: Jul 20, 2017
• Grant date: Oct 18, 2022
• Expiry date: Jul 10, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/062
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.