Quinazolinones that inhibit the formation of tau oligomers and their method of use
US11472776B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Dec 18, 2017 |
| Grant date | Oct 18, 2022 |
| Priority date | — |
| Expiry date | Dec 18, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.