Patent · US Active

Tobacco arsenic transport gene NtNIP7-1 and cloning method and applications thereof

US11473098B2 · kind B2 · utility

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Key dates

Filing dateSep 24, 2019
Grant dateOct 18, 2022
Priority date
Expiry dateMar 17, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/8243
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A tobacco arsenic transport gene NtNIP7-1 and a cloning method and application thereof are disclosed. A nucleotide sequence of the tobacco arsenic transport gene NtNIP7-1 is shown as SEQ ID: No. 1, and an encoded amino acid sequence thereof is shown as SEQ ID: No. 2. The cloning method of the tobacco arsenic transport gene NtNIP7-1 includes (S1) extracting RNA in tobacco, performing reverse transcription, and obtaining a first-strand cDNA; and (S2) taking the first-strand cDNA obtained by the reverse transcription as a template, synthesizing a specific primer according to sequences of the NtNIP7-1 gene, performing PCR amplification, recovering and purifying a product of the PCR amplification, and sequencing. In the present invention, inhibition of the expression of the tobacco endogenous gene NtNIP7-1 in tobacco plants is able to significantly reduce the arsenic content of tobacco leaves, and has broad application prospects in the field of low arsenic content breeding.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.