Method of identifying a compound which affects the multienzyme metabolic assembly of glucose metabolism and its association with cell cycle progression in cancer cells
US11474097B2 · kind B2 · utility
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Key dates
| Filing date | Jun 26, 2019 |
| Grant date | Oct 18, 2022 |
| Priority date | — |
| Expiry date | Aug 18, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91215
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A cell-based quantitative high-throughput screening assay to monitor the formation of PFK1-mEGFP clusters by the action of small molecules to identify small molecules that promote intracellular PFK1 clustering in a cell cycle-dependent manner and may be used to treat cancer.
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