ATP-binding cassette family coding polyribonucleotides and formulations thereof

US11479768B2 · kind B2 · utility

Assignee

• ethris GmbH · DE

Inventors

• Christian Plank · Wien, AT
• Carsten Rudolph · Krailling, DE
• Manish Kumar Aneja · Munich, DE
• Ludwig Weiss · Kissing, DE
• Mehrije Ferizi · Munich, DE
• Johannes Geiger · Munich, DE

Key dates

• Filing date: Jun 30, 2016
• Grant date: Oct 25, 2022
• Expiry date: Jun 30, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/51
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Polynucleotides encoding peptides, proteins, enzymes, and functional fragments thereof are disclosed. The polynucleotides of the disclosure can be effectively delivered to an organ, such as the lung, and expressed within cells of the organ. The polyribonucleotides of the disclosure can be used to treat a disease or condition associated with a gene of the ATP-binding cassette (ABC) family, such as ABCA3.