Compounds and methods useful in the treatment of a PRMT5-mediated disorder
US11485731B2 · kind B2 · utility
3Cited by
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20Claims
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Key dates
| Filing date | Mar 16, 2018 |
| Grant date | Nov 1, 2022 |
| Priority date | — |
| Expiry date | Mar 16, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure relates to compounds suitable for the inhibition of protein arginine methyl-transferase (PRMT), in particular PRMT5. These compounds may be for use as therapeutic agents, in particular, agents for use in the treatment and/or prevention of proliferative diseases, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.