Methods and systems for autoinduction of protein expression
US11485977B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Dec 19, 2014 |
| Grant date | Nov 1, 2022 |
| Priority date | — |
| Expiry date | Dec 19, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and systems for autoinduction of gene expression, without the need to add exogenous inducers. A dual genetic element system, which includes a first, high copy number genetic element comprising a first gene of interest that is under the control of an inducible promoter, and a second, low copy number genetic element comprising a gene encoding a transcriptional factor which, upon expression, regulates transcription from the inducible promoter, wherein activation of transcription from the inducible promoter does not require addition of an exogenous inducer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.