Multipore determination of fractional abundance of polynucleotide sequences in a sample
US11486873B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Apr 22, 2019 |
| Grant date | Nov 1, 2022 |
| Priority date | — |
| Expiry date | Jun 2, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and compositions for determining an improved estimate of the fractional abundance of target analytes (e.g., specific polynucleotide sequences) in a sample using a nanopore sensor having one or more nanopores-, e.g., by correcting errors inherent to identifying and correlating electrical signals to amounts of a target analyte or reference analyte in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.