Spherical microparticles with polyester walls

US11491090B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Ewelina Burakowska-Meise · Mannheim, DE
• Wolfgang Krause · Münstermaifeld, DE
• Patrick LEIBACH · Oberkochen, DE
• Karl Kolter · Ludwigshafen am Rhein, DE

Key dates

• Filing date: Oct 4, 2017
• Grant date: Nov 8, 2022
• Expiry date: Apr 13, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/007
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compositions of spherical microparticles composed of a wall material and at least one cavity that comprises a gas and/or a liquid, which have pores on the surface thereof, wherein the spherical microparticles have a mean particle diameter of 10-600 μm and wherein at least 80% of those microparticles, the particle diameter of which does not deviate from the mean particle diameter of the microparticles of the composition by more than 20%, each have on average at least 10 pores, the diameter of which is in the range from 1/5000 to ⅕ of the mean particle diameter, and, furthermore, the diameter of each of these pores is at least 20 nm,wherein the wall material consists of a composition comprising at least one aliphatic-aromatic polyester, and the wall material has a solubility at 25° C. of at least 50 g/l in dichloromethane, a method for the preparation thereof and also the use thereof.