Stem cell stimulating compositions and methods
US11491096B2 · kind B2 · utility
0Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2016 |
| Grant date | Nov 8, 2022 |
| Priority date | — |
| Expiry date | Dec 19, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.