Barbituric acid derivatives, their preparation and use thereof as leukocyte transmigration inhibitors and for treating inflammatory diseases, autoimmune diseases and cancer
US11492333B2 · kind B2 · utility
2Cited by
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23Claims
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Key dates
| Filing date | Aug 30, 2018 |
| Grant date | Nov 8, 2022 |
| Priority date | — |
| Expiry date | Oct 26, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are novel barbituric acid derivatives, their synthesis and use thereof in blocking leukocyte transmigration. The novel barbituric acid derivatives are useful for the treatment of disorders associated with leukocyte transmigration, such as for example inflammatory diseases and disorders, autoimmune diseases and disorders, and cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.