MTA-cooperative PRMT5 inhibitors
US11492351B2 · kind B2 · utility
0Cited by
0References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2020 |
| Grant date | Nov 8, 2022 |
| Priority date | — |
| Expiry date | Oct 16, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/1007
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds of Formula (I) to pharmaceutical compositions comprising compounds of Formula (I) and to methods of use thereof, such as methods of treating cancer using the compounds of Formula (I) and pharmaceutical compositions comprising those compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.