Patent · US Active

Protein modification of living cells using sortase

US11492590B2 · kind B2 · utility

5Cited by

17References

18Claims

0Family size

Assignee

Whitehead Institute For Biomedical Research · US

Inventors

Lee Kim Swee · Heidelberg, DE
Hidde L. Ploegh · Brookline, US

Key dates

Filing date	Apr 11, 2019
Grant date	Nov 8, 2022
Priority date	—
Expiry date	Jan 14, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/2207
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.