Patent · US Active

Methods and processes for non-invasive assessment of genetic variations

US11492659B2 · kind B2 · utility

3Cited by

41References

27Claims

0Family size

Assignee

Sequenom, Inc. · US

Inventors

Cosmin Deciu · San Diego, US
Zeljko Dzakula · San Diego, US
John Allen Tynan · San Diego, US
Grant Hogg · San Diego, US

Key dates

Filing date	Dec 10, 2018
Grant date	Nov 8, 2022
Priority date	—
Expiry date	Aug 5, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided herein are methods for determining fetal ploidy according to nucleic acid sequence reads. Nucleic acid sequence reads may be obtained from test sample nucleic acid comprising circulating cell-free nucleic acid from the blood of a pregnant female bearing a fetus. Fetal ploidy may be determined according to genomic section levels and a fraction of fetal nucleic acid in a test sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.