Variant nucleic acid libraries for GLP1 receptor
US11492727B2 · kind B2 · utility
3Cited by
589References
4Claims
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Key dates
| Filing date | Feb 26, 2020 |
| Grant date | Nov 8, 2022 |
| Priority date | — |
| Expiry date | Oct 12, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods and compositions relating to glucagon-like peptide-1 receptor (GLP1R) libraries having nucleic acids encoding for a scaffold comprising a GLP1R binding domain. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.