Ratiometric fluorescent probe, preparation method thereof, and application in detection of hydrogen peroxide
US11499094B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2022 |
| Grant date | Nov 15, 2022 |
| Priority date | — |
| Expiry date | Jan 14, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y40/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure provides a ratiometric fluorescent probe, a preparation method thereof, and an application in detection of hydrogen peroxide. In the present disclosure, MoOx QDs (nanoenzymes) and Co/Zn-MOFs both have catalytic activity, and the large specific surface area and porous structure of Co/Zn-MOFs can provide more binding sites for the contact between nanoenzymes and substrates. Moreover, Co/Zn-MOFs have high catalytic activity similar to natural enzymes. When nanoenzymes with fluorescent properties encounter Co/Zn-MOFs with similar catalytic activity, they will collide with a spark of “synergy catalysis”, and the fusion of the two plays a role of synergy catalysis; in addition, the uniform cavity of Co/Zn-MOFs can provide “hosts” for nanoenzymes, and Co/Zn-MOFs provide “anchors” for MoOx QDs, avoiding the aggregation of MoOx QDs and enhancing the stability of the probe.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.