Patent · US Active

Independently removable nucleic acid sequencing system and method

US11499191B2 · kind B2 · utility

1Cited by
24References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 20, 2018
Grant dateNov 15, 2022
Priority date
Expiry dateSep 16, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6869
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.