Patent · US Active

Light sheet microscope and method for determining the refractive indices of objects in the specimen space

US11500189B2 · kind B2 · utility

1Cited by

1References

15Claims

0Family size

Assignee

LEICA MICROSYSTEMS CMS GMBH · DE

Inventors

Alexander W. Weiss · Linden, DE
Christian Schumann · Gießen, DE
Ronja Capellmann · Wetzlar, DE

Key dates

Filing date	Mar 25, 2020
Grant date	Nov 15, 2022
Priority date	—
Expiry date	Mar 25, 2040

Classification

Technology area (CPC G)Physics
CPC primaryG02B21/34
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A light sheet microscope includes a sample chamber in which a cover slip or slide is arrangeable, which has a surface that defines a partially reflective interface and which has a further surface that defines a further partially reflective interface. The two interfaces are arranged at different distances from an objective. The light sheet microscope further includes an optical system having the objective facing toward the cover slip or slide, an illumination apparatus, which is designed to generate a light sheet, a sensor, and a processor. The two interfaces are formed in that two optical media are applicable in the sample chamber. The light sheet microscope forms a measuring device for acquiring a measured variable. The sensor is designed to acquire the intensities and/or the incidence locations of the two reflection light beams.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.