Patent · US Active

Eluent solution

US11504430B2 · kind B2 · utility

0Cited by

3References

9Claims

0Family size

Assignee

GE HEALTHCARE LIMITED · GB

Inventors

Torild Wickstrom · Oslo, NO
Anders Svadberg · Oslo, NO
Ole Kristian Hjelstuen · Oslo, NO
Dag M. Evje · Oslo, NO
Liane Ochsenfeld · Oslo, NO

Key dates

Filing date	Dec 21, 2011
Grant date	Nov 22, 2022
Priority date	—
Expiry date	Dec 21, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/0019
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a novel method for the preparation of 18F-fluoride (18F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation of 18F-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.