Patent · US Active

Metabolically stable N-acylaminooxadiazoles useful as antibacterial agents

US11505533B2 · kind B2 · utility

0Cited by

1References

32Claims

0Family size

Assignees

MICROBIOTIX, INC. · US
The Penn State Research Foundation · US

Inventors

Zachary D. Aron · Acton, US
Steven M. Kwasny · Blackstone, US
Matthew C. Torhan · Ayer, US
Jay P. Barbor · Worcester, US
Steven C. Cardinale · Hopedale, US
Michelle M. Butler · Auburn, US
Timothy Opperman · Somerville, US
Kenneth C. Keiler · Boalsburg, US

Key dates

Filing date	Aug 21, 2018
Grant date	Nov 22, 2022
Priority date	—
Expiry date	Aug 21, 2038

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of bacterial infections in humans and other mammals. A new class of small molecules is disclosed that inhibits the bacterial trans-translation/ribosome rescue mechanism and thus blocks infection of host cells by bacteria. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of bacterial infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.