Anthelmintic quinoline-3-carboxamide derivatives

US11505545B2 · kind B2 · utility

Assignee

• Bayer Animal Health GmbH · DE

Inventors

• Walter Hubsch · Wuppertal, DE
• Johannes Köbberling · Neuss, DE
• Adeline Köhler · Langenfeld, DE
• Hans-Georg Schwarz · Dorsten, DE
• Daniel KULKE · Leverkusen, DE
• Claudia WELZ · Goldkronach, DE
• Thomas ILG · Monheim, DE
• Kirsten BÖRNGEN · Neunburg vorm Wald, DE
• Wei Zhuang · Monheim, DE
• Nils Griebnow · Dormagen, DE
• Claudia Böhm · Hannover, DE
• Niels Lindner · Wuppertal, DE
• Maike Hink · Markgröningen, DE
• Ulrich Görgens · Ratingen, DE

Key dates

• Filing date: Oct 30, 2020
• Grant date: Nov 22, 2022
• Expiry date: Feb 15, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention covers new quinoline compounds of general formula (I): in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.