Patent · US Active

Cell culture medium

US11505784B2 · kind B2 · utility

0Cited by

4References

7Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Christoph CLEMENS · Biberach an der Riß, DE
Jochen Schaub · Biberach an der Riß, DE
Marie Link · Biberach an der Riß, DE
Peter Schorn · Langenau, DE
Torsten Schulz · Pinneberg, DE

Key dates

Filing date	Mar 31, 2016
Grant date	Nov 22, 2022
Priority date	—
Expiry date	Mar 7, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2511/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides a basal cell culture medium and a feed medium with novel amino acid ratios and/or iron choline citrate as iron carrier that result in improved performance of mammalian cell culture processes, such as CHO cultivation and protein production processes, in particular in increased product titer (e.g. of monoclonal antibodies). Also provided are methods for culturing mammalian cells and producing a protein of interest using said basal cell culture medium and optionally feed medium. The invention also provides for a medium platform that comprises (i) the basal cell culture medium and (ii) the feed medium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.