Methods and materials for producing 7-carbon monomers
US11505814B2 · kind B2 · utility
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Key dates
| Filing date | Nov 14, 2019 |
| Grant date | Nov 22, 2022 |
| Priority date | — |
| Expiry date | Nov 14, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y208/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.