Closed linear DNA production
US11505821B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Aug 16, 2017 |
| Grant date | Nov 22, 2022 |
| Priority date | — |
| Expiry date | Nov 7, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2531/125
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to improved processes for production of closed linear deoxyribonucleic acid (DNA), in particular cell-free enzymatic production of closed linear DNA molecules, preferably using a closed linear DNA as a template for DNA synthesis. The invention further relates to a novel closed linear DNA species, suitable for use as a template in the improved processes for production of closed linear DNA. Further, the invention pertains to the intermediate products of the processes, since this enables the production of larger quantities of closed linear DNA from the template than with methods known in the art.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.