Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
US11510970B2 · kind B2 · utility
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8References
21Claims
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Key dates
| Filing date | Feb 27, 2020 |
| Grant date | Nov 29, 2022 |
| Priority date | — |
| Expiry date | Feb 27, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/21001
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.