Covalent polymer-antigen conjugated particles
US11510996B2 · kind B2 · utility
2Cited by
9References
18Claims
0Family size
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Key dates
| Filing date | Dec 22, 2016 |
| Grant date | Nov 29, 2022 |
| Priority date | — |
| Expiry date | Dec 22, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6093
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions comprising tolerizing immune modified particles (TIMPs) and methods for using and making said TIMPs. In particular, carrier polymer is covalently conjugated with antigenic peptide before particle formation, which allows for exquisite control of particle size and antigen encapsulation (e.g., for use in eliciting induction of immunological tolerance).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.